Kentuckiana Integrative Medicine
405 E Court Ave #102, Jeffersonville, IN 47130
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Kentuckiana Integrative Medicine is a premier medical center and leader in regenerative, integrative, and functional medicine, located in Jeffersonville, IN, serving patients throughout Louisville, KY, and the U.S. who suffer from chronic pain, musculoskeletal issues, orthopedic injuries, mental health challenges like treatment-resistant depression, PTSD, anxiety, OCD, bipolar disorder, and conditions such as heart disease, neuropathy, fibromyalgia, autoimmune disorders, and addictions.
Founded and led by Dr. Rafael F.
Cruz MD, a board-certified physician with over 30 years of experience in emergency medicine, anesthesiology, and integrative medicine, the organization was established to provide advanced, personalized care that goes beyond traditional treatments.
Dr. Cruz's philosophy emphasizes a whole-person approach, addressing root causes of symptoms by considering lifestyle habits, mind, body, and soul to promote healing and well-being, blending conventional medicine with alternative therapies to restore health, energy, and function lost to aging, disease, or injury.
Services include regenerative injections such as bone marrow stem cell therapy and platelet-rich plasma for joint pain and injuries, IV nutrient infusions for immune support and detoxification, hormone replacement therapy for men and women, ketamine therapy for mental health including depression, anxiety, and suicidal ideation, prolotherapy and prolozone for musculoskeletal issues, chelation therapy for cardiovascular health, and holistic treatments like ozone therapy and medical weight loss.
The approach is evidence-based, utilizing innovative, non-surgical interventions like ultrasound-guided injections and personalized protocols to stimulate self-healing, enhance neuroplasticity, and improve outcomes for complex conditions, with a commitment to compassionate, family-centered care that empowers patients to regain quality of life.
What we treat
Treatment & Programs
Levels of Care
Kentuckiana Integrative Medicine provides highly specialized outpatient and telehealth services, accommodating patients with both mental health challenges and physiological conditions. The clinic’s continuum includes advanced options like Anesthesia Assisted Rapid Opiate Detoxification (AAROD) and customizable intensive outpatient paths. By offering 24/7 on-demand virtual consultations alongside in-office intensive care, Dr. Cruz and his team ensure flexible access to their progressive treatments.
Therapies
The clinical practice heavily utilizes intravenous therapies, pioneering the use of IV Ketamine to initiate what they call a brain reset for trauma and mood disorders. Alongside ketamine, clinicians administer regenerative modalities like Platelet Rich Plasma (PRP), messenger signaling cell therapies, and Prolozone injections for joint repair. Additionally, they incorporate innovative treatments such as Stellate Ganglion Blocks (SGB) and Plaquex therapy to address both neurological and cardiovascular challenges.
Addictions
Utilizing customized medical interventions, the clinic addresses serious substance use disorders, including dependencies on heroin, opioid prescriptions, cocaine, and methamphetamine. They also treat behavioral struggles like gambling addiction and support high-functioning professionals hiding their substance use. A standout feature is their use of the Sinclair Method for alcoholism and IV ketamine sedation for rapid opiate detox, aiming to displace narcotics safely and comfortably.
Conditions
Dr. Rafael F. Cruz and his staff specialize in complex, frequently misunderstood diagnoses such as treatment-resistant depression, bipolar disorder, and severe PTSD. The center also focuses heavily on life-altering physical ailments, including complex regional pain syndrome (CRPS), fibromyalgia, and debilitating neuropathy. By looking beyond standard psychiatric boundaries, their team works to reverse symptoms of obsessive-compulsive disorder (OCD) alongside chronic orthopedic pain.
Issues
Beyond acute psychiatric and addiction diagnoses, Kentuckiana Integrative Medicine assists individuals facing profound life stressors and complex medical hurdles. Staff members are highly experienced in treating the lingering effects of traumatic brain injuries (TBI), stroke recovery, and the debilitating fatigue of Long COVID. They also address practical health challenges, including erectile dysfunction, chronic non-healing wounds, and heavy metal toxicity, leaning on a whole-person perspective.
Programs
At the core of the treatment philosophy is their proprietary 5R Approach—focusing on the capacity to Reset, Reconnect, Recharge, Replenish, and Realign the mind, body, and spirit. For individuals battling alcoholism, they proudly employ the Sinclair Method, a highly effective pharmacological protocol aimed at safely extinguishing cravings. These structured methodologies move away from generic models, relying on evidence-based protocols to stimulate self-healing.
On-site
Amenities
To ensure IV therapy and procedures are as comfortable as possible, the facility features private, spa-like treatment rooms. Patients can relax in heated massage Lazy Boy chairs while listening to soothing meditation music and resting under warm blankets. The Jeffersonville office even offers comforting touches like "Sunny and Share," their soft stuffed pet companions, to help clients feel grounded and secure safely.
Coverage
Payment
The administrative team strives to make advanced therapies accessible by working with Traditional Medicare and commercial insurances for specific FDA-approved treatments, like hyaluronic gel knee injections. While cutting-edge IV Ketamine and regenerative injections remain largely self-pay, the front office utilizes third-party financing options to ensure out-of-pocket costs are manageable. It is important to note that they do not accept Medicaid or Medicare Advantage.
Eligibility
Who We Serve
Kentuckiana Integrative Medicine welcomes adults and seniors, maintaining a strong commitment to military veterans seeking specialized mental health interventions. Their restorative protocols attract professionals and high-functioning executives, as well as athletes looking for rapid recovery from sports injuries. Recognizing the unique physiological changes of aging, they also offer targeted hormone replacement regimens for men dealing with low testosterone and women enduring menopausal symptoms.
Populations Served
Additional Services
To support rapid and lasting improvements, the team provides robust wraparound services, including medication management via Naltrexone pellets, Vivitrol, and Suboxone. Customized IV nutritional infusions, such as the Myers-Gabys cocktail and high-dose Vitamin C, are integrated to detoxify the body and replenish cellular energy. Providers also incorporate cognitive behavioral planning and offer targeted telemedicine support to help patients maintain positive lifestyle changes.
About
Facility Info
Situated just five minutes from Louisville in the city of Jeffersonville, Indiana, this premier medical center blends conventional expertise with an integrative wellness environment. As a specialized for-profit organization, the clinic is equipped with advanced technologies like ultrasound and fluoroscopy to guide non-surgical interventions with pinpoint accuracy. This progressive clinical setting allows the medical team to administer complex alternative therapies seamlessly and safely.
Credentials
Accreditations
Reflecting a high standard of clinical excellence, Kentuckiana Integrative Medicine was the first clinic in the Kentuckiana region to receive Veteran Hospital approval as a Ketamine Treatment Center for treatment-resistant depression. Participating in this VA-approved network highlights the rigorous safety protocols maintained by Dr. Cruz and his specialized staff. This unique credential underscores their dedication to delivering clinically sound, life-saving therapies to those who served.
- 405 E Court Ave #102, Jeffersonville, IN 47130
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